Discovery of ‘click’ 1,2,3-triazolium salts as potential anticancer drugs

Abstract

In order to increase the effectiveness of cancer treatment, new compounds with potential anticancer activities are synthesized and screened. Here we present the screening of a new class of compounds, 1-(2-picolyl)-, 4-(2-picolyl)-, 1-(2-pyridyl)-, and 4-(2-pyridyl)-3-methyl-1,2,3-triazolium salts and ‘parent’ 1,2,3-triazole precursors.

Keywords

• triazoles
• triazolium salts
• anticancer activity
• cell cycle
• ros