Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion

Aleksandrs Kalnins, MD, MBA; Mrudula Penta, MD; Tarek El-Sawy, MD; Y. Joyce Liao, MD, PhD; Nancy Fischbein, MD; Michael Iv, MD

Radiology Case Reports (Feb 2019)

Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion

Aleksandrs Kalnins, MD, MBA,
Mrudula Penta, MD,
Tarek El-Sawy, MD,
Y. Joyce Liao, MD, PhD,
Nancy Fischbein, MD,
Michael Iv, MD

Affiliations

Aleksandrs Kalnins, MD, MBA: Advocate Christ Medical Center, Integrated Imaging Associates, 4440 W 95th St, Oak Lawn, IL 60453, USA; Corresponding author.
Mrudula Penta, MD: Division of Neuroradiology, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Room S-047, Stanford, CA 94305-5105, USA
Tarek El-Sawy, MD: Department of Ophthalmology, Stanford University School of Medicine, 2452 Watson Court, Palo Alto, CA 94303-5353, USA
Y. Joyce Liao, MD, PhD: Department of Ophthalmology, Stanford University School of Medicine, 2452 Watson Court, Palo Alto, CA 94303-5353, USA
Nancy Fischbein, MD: Division of Neuroradiology, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Room S-047, Stanford, CA 94305-5105, USA
Michael Iv, MD: Division of Neuroradiology, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Room S-047, Stanford, CA 94305-5105, USA

Journal volume & issue: Vol. 14, no. 2
pp. 226 – 229

Abstract

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Malignant optic glioma presents a clinical and diagnostic challenge, as early imaging findings overlap with other more common causes of optic nerve enhancement and enlargement, potentially leading to delay in diagnosis. This rare diagnosis carries an extremely poor prognosis, with death usually occurring within 1 year. We present a case of malignant optic glioma that was initially diagnosed as optic neuritis and central retinal vein occlusion, and we emphasize the importance of serial imaging and definitive biopsy to promote early diagnosis and treatment of this entity. Keywords: Head and neck radiology, Neuro-ophthalmology, Optic glioma, Glioblastoma multiforme (GBM), Optic nerve, Central retinal vein occlusion (CRVO)

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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