Antibiotics (Jul 2020)

Isolation and Biological Properties of the Natural Flavonoids Pectolinarin and Pectolinarigenin—A Review

  • Thamere Cheriet,
  • Balkeis Ben-Bachir,
  • Oumelkhir Thamri,
  • Ramdane Seghiri,
  • Ines Mancini

DOI
https://doi.org/10.3390/antibiotics9070417
Journal volume & issue
Vol. 9, no. 7
p. 417

Abstract

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Flavonoids are metabolites widely distributed in plants and commonly present in foods, such as fruits and vegetables. Pectolinarin, which belongs to the flavone subclass, has attracted considerable attention due to its presence in many medicinal plants. It has turned out to be a good biological agent especially due to its antioxidant, anti-inflammatory, antidiabetic, and antitumor activities, evaluated both in vitro and in vivo. Its aglycone, the metabolite pectolinarigenin, is also known for a series of biological properties including anti-inflammatory and antidiabetic effects. In the first overview on the two metabolites here presented, their collection, isolation and the results of their biological evaluation are reported.

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