Гинекология (Feb 2018)

Vitamin D and estrogen-dependent tumors

  • O A Gromova,
  • I Yu Torshin,
  • D E Frolova,
  • N P Lapochkina,
  • A N Gromov

Journal volume & issue
Vol. 20, no. 1
pp. 23 – 30

Abstract

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Vitamin D is characterized by undeniable antitumor properties that are important for both prevention and treatment of tumor diseases. The results of a systematic analysis of the molecular mechanisms of antitumor effects of vitamin D (inhibition of the Wnt/b-catenin cascade, the transcription factor WSTF) and the results of clinical studies of patients with estrogen-dependent tumors are presented, indicating the promise of combined use of estrogen and vitamin D.

Keywords