Translational Psychiatry (Jul 2022)

Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic

  • Yu-Chen Li,
  • Wei Bai,
  • Hong Cai,
  • Yuxuan Wu,
  • Ling Zhang,
  • Yan-Hong Ding,
  • Juan-Juan Yang,
  • Xiangdong Du,
  • Zhen-Tao Zeng,
  • Chang-Mou Lu,
  • Ke-Xin Feng,
  • Wen-Fang Mi,
  • Lan Zhang,
  • Huan-Zhong Liu,
  • Lloyd Balbuena,
  • Teris Cheung,
  • Zhaohui Su,
  • Feng-Rong An,
  • Yu-Tao Xiang

DOI
https://doi.org/10.1038/s41398-022-02045-2
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 7

Abstract

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Abstract The coronavirus disease 2019 (COVID-19) pandemic has a disproportionate impact on vulnerable subpopulations, including those with severe mental illness (SMI). This study examined the one-year prevalence of suicidal ideation (SI), suicide plans (SP), and suicide attempts (SA) in bipolar disorder (BD) and schizophrenia (SCZ) patients during the pandemic. Prevalence rates were compared between the two disorders and associated factors were examined. A survey was conducted in six tertiary psychiatric hospitals and psychiatric units. People with a diagnosis of BD or SCZ were invited to participate. SI, SP, and SA (suicidality for short) were assessed and associated factors were examined using binary logistical regression. The 1-year prevalence of SI, SP and SA in BD patients were 58.3%, (95% CI: 54.1–62.6%), 38.4% (95% CI: 34.3–42.6%) and 38.6% (95% CI: 34.5–42.8%), respectively, which were higher than the corresponding figures in SCZ patients (SI: 33.2%, 95% CI: 28.6–37.8%; SP: 16.8%, 95% CI: 13.2–20.5%; SA: 19.4%, 95% CI: 15.5–23.3%). Patients with younger age, experience of cyberbullying, a history of SA among family or friends, a higher fatigue and physical pain score, inpatient status, and severe depressive symptoms were more likely to have suicidality. The COVID-19 pandemic was associated with increased risk of suicidality, particularly in BD patients. It is of importance to regularly screen suicidality in BD and SCZ patients during the pandemic even if they are clinically stable.