Scientific Reports (Nov 2023)

Sexual dysfunction in women with breast cancer of Northeast Brazil: a retrospective longitudinal study

  • Thais Sousa Rodrigues Guedes,
  • Marcello Barbosa Otoni Gonçalves Guedes,
  • Johnnatas Mikael Lopes,
  • Rebeca de Castro Santana,
  • Jamily Borba de Vasconcelos,
  • Eva Regina de Medeiros,
  • Vitor Leandro da Cunha,
  • Amanda Almeida Gomes Dantas,
  • Javier Jerez-Roig,
  • Dyego Leandro Bezerra de Souza

DOI
https://doi.org/10.1038/s41598-023-47684-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

Read online

Abstract Breast cancer treatment leads to physical and psychological changes. The aim of this study was to analyze the incidence of sexual dysfunction and its risk factors in women diagnosed with breast cancer. This retrospective cohort study included women diagnosed and treated for breast cancer (exposed group, n = 90) and healthy women (non-exposed group, n = 93). Data were collected from February 2019 to October 2021 in the state of Rio Grande do Norte (Northeast Brazil), from medical records and using the Female Sexual Function Index (FSFI) questionnaire. Data were collected from medical records and using the Female Sexual Function Index (FSFI) questionnaire. Primary outcomes were analyzed using binary logistic regression. The Mann–Whitney test was used to analyze FSFI domains between groups. The exposed group had a 74% incidence of sexual dysfunction and 3.9 times increased chances of having sexual dysfunction compared with the non-exposed group (OR 3.9, CI 1.8 to 8.2, p < 0.001). Presence of comorbidities increased the chances of sexual dysfunction by 2.5 times (OR 2.5, CI 1.2 to 4.9, p = 0.009). Women diagnosed and treated for breast cancer had a higher incidence of sexual dysfunction than healthy women. Furthermore, comorbidities also increased the chances of sexual dysfunction regardless of exposure to breast cancer.