Zaporožskij Medicinskij Žurnal (Dec 2013)
Spermatogenesis after extreme hyperthermal, hypothermal and traumatic infl uences and the possibility of its drug correction in the experiment
Abstract
Introduction Infertility is an important component of the total medical-demographic problems, which accumulates the entire range of factors of socio - economic, behavioral, genetic and natural-climatic, ecological Genesis. Male infertility is founded in 35-40% of the causes of the couple infertility. Attention to the male reproductive function is increasing and it is caused by the appearance of a large number of messages about the increasing incidence of diseases of male reproductive organs, reduction of quantitative and qualitative characteristics of the semen, the significance of the male pathology in the formation of infertility in marriage. Research objective To analyze the status of spermatogenesis after extreme hyperthermal, hypothermal and traumatic effects and the possibility of drug correction in the experiment. Materials and methods Semantic evaluation of scientific documents, comparison, as well as the structural-logical analysis were used. In the literature there are reports of violation of the structure of the sperm. Causes may include testicular injury, surgery or epidemic parotitis (mumps) in the past, severe allergic reactions, the impact of radiation, the use of some drugs. Chronic hyperthermia causes changes of all structural components of the tissues of the testicles, which slows down the processes of spermatogenesis. Conclusions There are several reasons for male infertility. Stress, fear of sexual or family relations, in some men are the unwillingness of paternity. Injury or genital mutilation, primarily on the testicles can lead to the violation of the gematotestcular barrier with the formation of specific substances, which destroy tubules of the testicle. Antisperm antibodies completely destroys tubular apparatus. Study of spermatogenesis in experimental models is important and promising direction. It gives both theoretical and practical points of view on the development of methods of prevention and medical correction of disorders of reproductive function.
Keywords
