Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis

Zhicheng Cui; Xiaojun Li; Joonyoung Shin; Howard Gamper; Ya-Ming Hou; James C. Sacchettini; Junjie Zhang

doi:10.1038/s41467-022-28078-1

Nature Communications (Jan 2022)

Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis

Zhicheng Cui,
Xiaojun Li,
Joonyoung Shin,
Howard Gamper,
Ya-Ming Hou,
James C. Sacchettini,
Junjie Zhang

Affiliations

Zhicheng Cui: Department of Biochemistry and Biophysics, Texas A&M University
Xiaojun Li: Department of Biochemistry and Biophysics, Texas A&M University
Joonyoung Shin: Department of Biochemistry and Biophysics, Texas A&M University
Howard Gamper: Department of Biochemistry and Molecular Biology, Thomas Jefferson University
Ya-Ming Hou: Department of Biochemistry and Molecular Biology, Thomas Jefferson University
James C. Sacchettini: Department of Biochemistry and Biophysics, Texas A&M University
Junjie Zhang: Department of Biochemistry and Biophysics, Texas A&M University

DOI: https://doi.org/10.1038/s41467-022-28078-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

Read online

The authors present structures of the MtbEttA protein bound to or free of the ribosome from Mycobacterium tuberculosis under different nucleotide states, which provide insights into the mechanism of translational regulation by EttA-like proteins.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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