Frontiers in Oncology (Jul 2023)

Pediatric diencephalic tumors: a constellation of entities and management modalities

  • Soniya N. Pinto,
  • Jason Chiang,
  • Ibrahim Qaddoumi,
  • David Livingston,
  • Asim Bag

DOI
https://doi.org/10.3389/fonc.2023.1180267
Journal volume & issue
Vol. 13

Abstract

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The diencephalon is a complex midline structure consisting of the hypothalamus, neurohypophysis, subthalamus, thalamus, epithalamus, and pineal body. Tumors arising from each of these diencephalic components differ significantly in terms of biology and prognosis. The aim of this comprehensive review is to describe the epidemiology, clinical symptoms, imaging, histology, and molecular markers in the context of the 2021 WHO classification of central nervous system neoplasms. We will also discuss the current management of each of these tumors.

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