Clinical Case Reports (May 2023)

Hairy cell leukemia with isolated bone lesions

  • Laura Cailly,
  • Cécile Gruchet,
  • Elsa Maitre,
  • Stephanie Guidez,
  • Vincent Delwail,
  • Thomas Systchenko,
  • Niels Moya,
  • Florence Sabirou,
  • Anthony Levy,
  • Arthur Bobin,
  • Hélène Gardeney,
  • Laly Nsiala,
  • Mathilde Vonfeld,
  • Aurélia Chacon,
  • Aurélien Pichon,
  • Sabrina Bouyer,
  • Caroline Baslé,
  • Elodie Dindinnaud,
  • Jean‐Claude Chomel,
  • Anna Raimbault,
  • Florence Borde‐Mougenot,
  • Xavier Troussard,
  • Cécile Tomowiak

DOI
https://doi.org/10.1002/ccr3.7343
Journal volume & issue
Vol. 11, no. 5
pp. n/a – n/a

Abstract

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Key Clinical Message 18F‐FDG PET/CT has clinical relevance in HCL at diagnosis and for the follow‐up of patients treated, especially in case of atypical presentations such as bone involvements (which are probably underestimated) and poor bone marrow infiltration. Abstract Bone lesions are rarely reported in Hairy Cell Leukemia (HCL). We report two BRAFV600E mutated HCL patients presented bone lesions at foreground, poor bone marrow involvement, and the important role 18F‐FDG PET/CT played in their management. We discuss the crucial role that 18F‐FDG PET/CT could play in HCL routine practice.

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