SIRT6 promotes autophagy through direct interaction with ULK1 and competitive binding to PUMA

• Zhongguang Wu,
• Lanhui Hong,
• Guang Luo,
• Siyao Lu,
• Yanqiu Li,
• Jiangang Wang,
• Yingjie Zhang,
• Lingling Zhang

Affiliations

Zhongguang Wu

Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China

Lanhui Hong

Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China

Guang Luo

Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China; School of Biomedical Sciences, Hunan University, Changsha, Hunan 410082, China

Siyao Lu

Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China; School of Biomedical Sciences, Hunan University, Changsha, Hunan 410082, China

Yanqiu Li

Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China

Jiangang Wang

Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Corresponding author.

Yingjie Zhang

School of Biomedical Sciences, Hunan University, Changsha, Hunan 410082, China; Corresponding author. School of Biomedical Sciences, Hunan University, Changsha, Hunan 410082, China.

Lingling Zhang

Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China; Corresponding author. Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China.