Variants of gallbladder adenocarcinomas: Five case reports

Abstract

Conventional adenocarcinomas comprise of about 90% of all gallbladder neoplasms; among them, pancreatobiliary is the most common phenotype followed by intestinal and gastric foveolar types. Papillary variant is the second most common form of adenocarcinoma affecting the gallbladder. Mucinous adenocarcinoma and signet-ring cell carcinoma are rarer variants with grave prognoses. We report five cases of gallbladder neoplasms with four different histopathological features. (1) To report the rare neoplasms of the gallbladder for the future researches on their histopathology-based targeted therapy. (2) To describe the clinico-pathogical characteristics of the rare variants of gallbladder neoplasm.

Keywords

• Gallbladder
• mucinous adenocarcinoma
• papillary adenocarcinoma
• signet-ring cell