A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma

Samender Randhawa MD; Jessica Pinsker BS; Madhurya Amirapu MBBS; Metlapalli Venkata Sravanthi MBBS; Prashanth Ashok Kumar MBBS; Komal Akhtar MD

doi:10.1177/23247096221103385

Journal of Investigative Medicine High Impact Case Reports (Jun 2022)

A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma

Samender Randhawa MD,
Jessica Pinsker BS,
Madhurya Amirapu MBBS,
Metlapalli Venkata Sravanthi MBBS,
Prashanth Ashok Kumar MBBS,
Komal Akhtar MD

Affiliations

Samender Randhawa MD: State University of New York Upstate Medical University, Syracuse, USA
Jessica Pinsker BS: State University of New York Upstate Medical University, Syracuse, USA
Madhurya Amirapu MBBS: State University of New York Upstate Medical University, Syracuse, USA
Metlapalli Venkata Sravanthi MBBS: State University of New York Upstate Medical University, Syracuse, USA
Prashanth Ashok Kumar MBBS: State University of New York Upstate Medical University, Syracuse, USA
Komal Akhtar MD: State University of New York Upstate Medical University, Syracuse, USA

DOI: https://doi.org/10.1177/23247096221103385
Journal volume & issue: Vol. 10

Abstract

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Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene rearrangement and are associated with TSC with a preference for an occurrence at a younger age. We report a case of a young male who had progressive chronic hip pain and was found to have a TFE3 -associated PEComa in his pelvic region.

Published in Journal of Investigative Medicine High Impact Case Reports

ISSN: 2324-7096 (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Medicine (General); Medicine: Pathology
Website: https://journals.sagepub.com/home/hic

About the journal