Rollover Cyclometalation vs Nitrogen Coordination in Tetrapyridyl Anticancer Gold(III) Complexes: Effect on Protein Interaction and Toxicity

• Xue-Quan Zhou,
• Imma Carbo-Bague,
• Maxime A. Siegler,
• Jonathan Hilgendorf,
• Uttara Basu,
• Ingo Ott,
• Rongfang Liu,
• Liyan Zhang,
• Vadde Ramu,
• Adriaan P. IJzerman,
• Sylvestre Bonnet

Affiliations

Xue-Quan Zhou

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Imma Carbo-Bague

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Maxime A. Siegler

Department of Chemistry, Johns Hopkins University, Baltimore, Maryland, United States

Jonathan Hilgendorf

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Uttara Basu

Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany

Ingo Ott

Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Braunschweig, Germany

Rongfang Liu

Division of Drug Discovery & Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Liyan Zhang

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Vadde Ramu

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Adriaan P. IJzerman

Division of Drug Discovery & Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Sylvestre Bonnet

Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands