Scientific evidences of anticancer potential of medicinal plants

Abstract

Cancer being a life treating ailment is the second reason of death universally. The growing threats of medication-resistant cancers indicates an crucial need for the improvement of more effective anticancer agents. Herbal medication offers very reasonable alternate to modern medicine against cancer. The investigation of natural products is a valued method for the detection and expansion of newer biologically dynamic compounds having exclusive assemblies and pathways. This work reviews certain medicinal plant with active phytochemicals, methodology of researches and their pharmacological characteristics. This work is created after careful literature review directed through relevant exploration of keywords in Clarivate Analytical, Web of Science, Scopus, Google Scholar, Science Direct, PubMed, MDPI, and Google Academic. This study was planned to accumulate the record of plants having anticancer activity and the evidences supporting their usage in cancer treatment. Fifty plants were selected based on their potenty as anticancer compounds. The thorough research studies exposed that plants and its phytochemicals can play a crucial role against oral, breast, lung, cervical, colon, stomach, hepatic cancers. The in vitro researches displayed that the plant secondary metabolites in extracts causes inhibition of cancer cell through DNA mutilation as well as stimulation of apoptosis-tempting enzymes in different models.

Keywords

• Colorectal
• Prostate
• Bladder
• Tinospora cordifolia
• Withanaia somnifera