Human Atypical Monkeypox: Early Warning for Global Outbreak?

Abstract

Abstract. Monkeypox is usually considered as a zoonosis caused by monkeypox virus with potential threat to public health in the post–smallpox era. The recent outbreak of monkeypox began in May 7, 2022, and has been found in many countries out of Africa. The World Health Organization declared that this endemic is an “atypical” phenomenon with definite human-to-human transmission. To understand the situation more clearly, this review briefly summarizes the epidemiologic and clinical characteristics of the disease and highlights the clinical management and preventive strategies.