A distinct inner nuclear membrane proteome in <i>Saccharomyces cerevisiae</i> gametes

Abstract

AbstractThe inner nuclear membrane (INM) proteome regulates gene expression, chromatin organization, and nuclear transport; however, it is poorly understood how changes in INM protein composition contribute to developmentally regulated processes, such as gametogenesis. We conducted a screen to determine how the INM proteome differs between mitotic cells and gametes. In addition, we used a strategy that allowed us to determine if spores synthesize their INM proteins de novoSaccharomyces cerevisiaede novo