Communications Materials (Sep 2020)

The role of valve stiffness in the insurgence of deep vein thrombosis

  • Zoe Schofield,
  • Hosam Alden Baksamawi,
  • Joana Campos,
  • Alessio Alexiadis,
  • Gerard B. Nash,
  • Alexander Brill,
  • Daniele Vigolo

DOI
https://doi.org/10.1038/s43246-020-00066-2
Journal volume & issue
Vol. 1, no. 1
pp. 1 – 10

Abstract

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Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.