mBio (Jun 2021)

Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium

  • Sushmita Sridhar,
  • Sally Forrest,
  • Derek Pickard,
  • Claire Cormie,
  • Emily A. Lees,
  • Nicholas R. Thomson,
  • Gordon Dougan,
  • Stephen Baker

DOI
https://doi.org/10.1128/mBio.01093-21
Journal volume & issue
Vol. 12, no. 3

Abstract

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Antimicrobial resistance is a critical concern in global health. In particular, there is rising resistance to fluoroquinolones, such as ciprofloxacin, a first-line antimicrobial for many Gram-negative pathogens.