Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading

Christopher A. Brosnan; Alexander J. Palmer; Steven Zuryn

doi:10.1038/s41467-021-22503-7

Nature Communications (Apr 2021)

Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading

Christopher A. Brosnan,
Alexander J. Palmer,
Steven Zuryn

Affiliations

Christopher A. Brosnan: Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland
Alexander J. Palmer: Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland
Steven Zuryn: Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland

DOI: https://doi.org/10.1038/s41467-021-22503-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 16

Abstract

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C. elegans miRNAs associate with AGO proteins ALG-1 and ALG-2. Here the authors provide a map of miRNAs loaded into ALG-1 and ALG-2 from intestine, body wall muscles and nervous system in C. elegans providing insights into spatial and temporal AGO loading flexibility.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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