Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders

Mary Emma Gorham Bigelow; Brian G. Jamieson; Chi On Chui; Yufei Mao; Kyeong-Sik Shin; Tony Jun Huang; Po-Hsun Huang; Liqiang Ren; Bishow Adhikari; Jue Chen; Erin Iturriaga

doi:10.1109/JTEHM.2016.2593920

IEEE Journal of Translational Engineering in Health and Medicine (Jan 2016)

Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders

Mary Emma Gorham Bigelow,
Brian G. Jamieson,
Chi On Chui,
Yufei Mao,
Kyeong-Sik Shin,
Tony Jun Huang,
Po-Hsun Huang,
Liqiang Ren,
Bishow Adhikari,
Jue Chen,
Erin Iturriaga

Affiliations

Mary Emma Gorham Bigelow: ORCiD; Diagnostic Biochips, Inc., Glen Burnie, MD, USA
Brian G. Jamieson: Diagnostic Biochips, Inc., Glen Burnie, MD, USA
Chi On Chui: Electrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USA
Yufei Mao: Electrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USA
Kyeong-Sik Shin: Electrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USA
Tony Jun Huang: Bioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USA
Po-Hsun Huang: Bioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USA
Liqiang Ren: Bioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USA
Bishow Adhikari: National Heart, Lung, and Blood Institute, Bethesda, MD, USA
Jue Chen: National Heart, Lung, and Blood Institute, Bethesda, MD, USA
Erin Iturriaga: National Heart, Lung, and Blood Institute, Bethesda, MD, USA

DOI: https://doi.org/10.1109/JTEHM.2016.2593920
Journal volume & issue: Vol. 4
pp. 1 – 10

Abstract

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The commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition can be interrogated and monitored. Point of care technologies may enable access to rapid and cost-effective interrogation of a patient's health condition in near real time. Currently, physiological data are largely limited to single-time-point collection at the hospital or clinic, whereas critical information on some conditions must be collected in the home, when symptoms occur, or at regular intervals over time. A variety of HLBS disorders are highly dependent on transient variables, such as patient activity level, environment, time of day, and so on. Consequently, the National Heart Lung and Blood Institute sponsored a request for applications to support the development and commercialization of novel point-of-care technologies through small businesses (RFA-HL-14-011 and RFA-HL-14-017). Three of the supported research projects are described to highlight particular point-of-care needs for HLBS disorders and the breadth of emerging technologies. While significant obstacles remain to the commercialization of such technologies, these advancements will be required to achieve precision medicine.

Published in IEEE Journal of Translational Engineering in Health and Medicine

ISSN: 2168-2372 (Online)
Publisher: IEEE
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Medicine: Medicine (General): Medical technology
Website: https://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=6221039

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Abstract

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