Communications Biology (Oct 2021)

AdRoit is an accurate and robust method to infer complex transcriptome composition

  • Tao Yang,
  • Nicole Alessandri-Haber,
  • Wen Fury,
  • Michael Schaner,
  • Robert Breese,
  • Michael LaCroix-Fralish,
  • Jinrang Kim,
  • Christina Adler,
  • Lynn E. Macdonald,
  • Gurinder S. Atwal,
  • Yu Bai

DOI
https://doi.org/10.1038/s42003-021-02739-1
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 14

Abstract

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Yang et al. present AdRoit, a method for deconvoluting bulk RNA sequencing and spatial transcriptomics data. AdRoit performs well on datasets from complex tissues with many different cell types.