Nature Communications (Oct 2018)
Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting
- Arthur Charles-Orszag,
- Feng-Ching Tsai,
- Daria Bonazzi,
- Valeria Manriquez,
- Martin Sachse,
- Adeline Mallet,
- Audrey Salles,
- Keira Melican,
- Ralitza Staneva,
- Aurélie Bertin,
- Corinne Millien,
- Sylvie Goussard,
- Pierre Lafaye,
- Spencer Shorte,
- Matthieu Piel,
- Jacomine Krijnse-Locker,
- Françoise Brochard-Wyart,
- Patricia Bassereau,
- Guillaume Duménil
Affiliations
- Arthur Charles-Orszag
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- Feng-Ching Tsai
- Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
- Daria Bonazzi
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- Valeria Manriquez
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- Martin Sachse
- Ultrapole, Institut Pasteur
- Adeline Mallet
- Ultrapole, Institut Pasteur
- Audrey Salles
- Imagopole, Institut Pasteur
- Keira Melican
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- Ralitza Staneva
- Institut Curie, PSL Research University, CNRS, UMR 144
- Aurélie Bertin
- Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
- Corinne Millien
- Paris Cardiovascular Research Center
- Sylvie Goussard
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- Pierre Lafaye
- Antibody Engineering, Institut Pasteur
- Spencer Shorte
- Imagopole, Institut Pasteur
- Matthieu Piel
- Systems Biology of Cell Polarity and Cell Division, Institut Pierre-Gilles De Gennes
- Jacomine Krijnse-Locker
- Ultrapole, Institut Pasteur
- Françoise Brochard-Wyart
- Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
- Patricia Bassereau
- Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
- Guillaume Duménil
- Pathogenesis of Vascular Infections Unit, INSERM, Institut Pasteur
- DOI
- https://doi.org/10.1038/s41467-018-06948-x
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 14
Abstract
Meningococci remodel the plasma membrane of host cells during infection. Here, Charles-Orszag et al. show that plasma membrane remodeling occurs independently of F-actin, along meningococcal type IV pili fibers, by a physical mechanism that they term ‘one-dimensional’ membrane wetting.
