Frontiers in Neuroscience (May 2023)
Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice
- Bernardo A. Arús,
- Bernardo A. Arús,
- Bernardo A. Arús,
- Bernardo A. Arús,
- Bernardo A. Arús,
- Emily D. Cosco,
- Emily D. Cosco,
- Joycelyn Yiu,
- Ilaria Balba,
- Thomas S. Bischof,
- Thomas S. Bischof,
- Thomas S. Bischof,
- Thomas S. Bischof,
- Thomas S. Bischof,
- Ellen M. Sletten,
- Oliver T. Bruns,
- Oliver T. Bruns,
- Oliver T. Bruns,
- Oliver T. Bruns,
- Oliver T. Bruns
Affiliations
- Bernardo A. Arús
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Bernardo A. Arús
- German Cancer Research Center (DKFZ), Heidelberg, Germany
- Bernardo A. Arús
- National Center for Tumor Diseases (NCT/UCC), Dresden, Germany
- Bernardo A. Arús
- Medizinische Fakultät and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Bernardo A. Arús
- Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany
- Emily D. Cosco
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Emily D. Cosco
- Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, United States
- Joycelyn Yiu
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Ilaria Balba
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Thomas S. Bischof
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Thomas S. Bischof
- German Cancer Research Center (DKFZ), Heidelberg, Germany
- Thomas S. Bischof
- National Center for Tumor Diseases (NCT/UCC), Dresden, Germany
- Thomas S. Bischof
- Medizinische Fakultät and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Thomas S. Bischof
- Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany
- Ellen M. Sletten
- Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, United States
- Oliver T. Bruns
- Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, Germany
- Oliver T. Bruns
- German Cancer Research Center (DKFZ), Heidelberg, Germany
- Oliver T. Bruns
- National Center for Tumor Diseases (NCT/UCC), Dresden, Germany
- Oliver T. Bruns
- Medizinische Fakultät and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Oliver T. Bruns
- Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany
- DOI
- https://doi.org/10.3389/fnins.2023.1135494
- Journal volume & issue
-
Vol. 17
Abstract
Extracting biological information from awake and unrestrained mice is imperative to in vivo basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.
Keywords
