Nature Communications (Aug 2018)

Single-molecule detection with a millimetre-sized transistor

  • Eleonora Macchia,
  • Kyriaki Manoli,
  • Brigitte Holzer,
  • Cinzia Di Franco,
  • Matteo Ghittorelli,
  • Fabrizio Torricelli,
  • Domenico Alberga,
  • Giuseppe Felice Mangiatordi,
  • Gerardo Palazzo,
  • Gaetano Scamarcio,
  • Luisa Torsi

DOI
https://doi.org/10.1038/s41467-018-05235-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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The sensing capability of nanometric transducers designed for label-free single molecule detection has been limited by the small number of recognition elements. Here, the authors demonstrate a millimetre-sized field effect transistor capable of selective single-molecule Immunoglobulin-G detection.