Poly caprolactone/titanium dioxide nanofiber coating on AM50 alloy for biomedical application

Abstract

Poly caprolactone (PCL) and Poly caprolactone/TiO2 (PCL/TiO2) composite nanofiber with different weight percentage compositions (2 wt%, 4 wt% and 6 wt%) of TiO2 were prepared and coated over AM50 alloy using electrospinning technique. The surface morphology and elemental composition result confirms that the PCL/TiO2 composite nanofiber fiber were successfully electrospun on the surface of AM50 alloy. The degradation behavior of PCL and PCL/6 wt% TiO2 coated AM50 alloy was studied by immersing in Simulated Body Fluid (SBF) solution. The electrochemical and cell proliferation studies reveals that the cellular behavior of PCL and PCL/6 wt% TiO2 composite nanofiber exhibited good support for cell proliferation with enhanced corrosion resistance of AM50 alloy in SBF solution.

Keywords

• Electrospinning
• AM50 alloy
• Polycaprolactone
• Biocompatible
• Corrosion resistance
• Electrochemical studies