Diagnostics (Sep 2024)

A Unique Case of Unilateral Pseudogynecomastia

  • Ismini Kountouri,
  • Ioannis Katsarelas,
  • Eftychia Kokkali,
  • Amyntas Giotas,
  • Christos Gkogkos,
  • Dimitrios Chatzinas,
  • Panagiotis Nachopoulos,
  • Afroditi Faseki,
  • Alexandra Panagiotou,
  • Athanasios Polychronidis,
  • Miltiadis Chandolias,
  • Nikolaos Gkiatas,
  • Dimitra Manolakaki,
  • Periklis Dimasis

DOI
https://doi.org/10.3390/diagnostics14182058
Journal volume & issue
Vol. 14, no. 18
p. 2058

Abstract

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Background/Objectives: Gynecomastia is a common condition characterized by the benign enlargement of male breast tissue, often resulting from hormonal imbalances. A rare variant, unilateral pseudogynecomastia, involves enlargement due to adipose tissue accumulation without glandular proliferation and can be associated with occupational factors. Methods: We report the case of a 45-year-old male mechanic presenting with unilateral enlargement of the left breast. The patient reported daily microtrauma on his left axilla and chest wall. The clinical evaluation and imaging revealed lipomatosis with pronounced fibrous tissue and no glandular tissue involvement. The hormonal assays were within the normal limits. The patient underwent surgical excision of excess adipose tissue using the Kornstein technique, preserving the nipple–areola complex. Results: The histopathological examination confirmed the absence of malignancy. The postoperative recovery was uneventful, and the follow-up examination at 12 months demonstrated a symmetrical breast appearance with no recurrence. This case underscores the importance of differentiating pseudogynecomastia from true gynecomastia and recognizing potential occupational risks. Surgical management using techniques that preserve the nipple–areola complex can achieve excellent cosmetic outcomes.

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