PLoS ONE (Jan 2015)

Incidence of Medically-Attended Norovirus-Associated Acute Gastroenteritis in Four Veteran's Affairs Medical Center Populations in the United States, 2011-2012.

  • Scott P Grytdal,
  • David Rimland,
  • S Hannah Shirley,
  • Maria C Rodriguez-Barradas,
  • Matthew Bidwell Goetz,
  • Sheldon T Brown,
  • Cynthia Lucero-Obusan,
  • Mark Holodniy,
  • Christopher Graber,
  • Umesh Parashar,
  • Jan Vinjé,
  • Ben Lopman

DOI
https://doi.org/10.1371/journal.pone.0126733
Journal volume & issue
Vol. 10, no. 5
p. e0126733

Abstract

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An estimated 179 million acute gastroenteritis (AGE) illnesses occur annually in the United States. The role of noroviruses in hospital-related AGE has not been well-documented in the U. S. We estimated the population incidence of community- acquired outpatient and inpatient norovirus AGE encounters, as well as hospital-acquired inpatient norovirus AGE among inpatients at four Veterans Affairs (VA) Medical Centers (VAMCs). Fifty (4%) of 1,160 stool specimens collected ≤7 days from symptom onset tested positive for norovirus. During a one year period, the estimated incidence of outpatient, community- and hospital-acquired inpatient norovirus AGE was 188 cases, 11 cases, and 54 cases/ 100,000 patients, respectively. This study demonstrates the incidence of outpatient and community- and hospital-acquired inpatient norovirus AGE among the VA population seeking care at these four VAMCs.