Dataset on the effects of CYB5D2 on the distribution of HeLa cervical cancer cell cycle

Yanyun Xie; Yen Ting Shen; Anil Kapoor; Diane Ojo; Fengxiang Wei; Jason De Melo; Xiaozeng Lin; Nicholas Wong; Judy Yan; Lijian Tao; Pierre Major; Damu Tang

Data in Brief (Mar 2016)

Dataset on the effects of CYB5D2 on the distribution of HeLa cervical cancer cell cycle

Yanyun Xie,
Yen Ting Shen,
Anil Kapoor,
Diane Ojo,
Fengxiang Wei,
Jason De Melo,
Xiaozeng Lin,
Nicholas Wong,
Judy Yan,
Lijian Tao,
Pierre Major,
Damu Tang

Affiliations

Yanyun Xie: Division of Nephrology, Department of Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, PR China; Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Yen Ting Shen: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Anil Kapoor: Father Sean O’Sullivan Research Institute, Canada; Department of Surgery, McMaster University, Hamilton, Ontario, Canada
Diane Ojo: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Fengxiang Wei: The Genetics Laboratory, Institute of Women and Children’s Health, Longgang District, Shenzhen, Guangdong, PR China; ZhunYi Medical University, Zhunyi, Guizhou, PR China
Jason De Melo: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Xiaozeng Lin: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Nicholas Wong: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Judy Yan: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada
Lijian Tao: Division of Nephrology, Department of Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, PR China
Pierre Major: Division of Medical Oncology, Department of Oncology, McMaster University, Hamilton, Ontario, Canada
Damu Tang: Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O’Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph’s Hospital, Canada; Corresponding author at: Division of Nephrology, Department of Medicine, McMaster University, Canada.

Journal volume & issue: Vol. 6
pp. 811 – 816

Abstract

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We have recently reported that CYB5D2 plays a role in suppression of cervical cancer tumorigenesis, “CYB5D2 displays tumor suppression activities towards cervical cancer” [1]. We provide the accompany data here describing the effects of CYB5D2 overexpression and addition of recombinant CYB5D2 on HeLa cell cycle distribution. Furthermore, we will present the conditions used to specifically determine CYB5D2 expression in primary cervical and cervical cancer tissues using immunohistochemistry (IHC) and the patient cohort involved in assessing the CYB5D2 protein levels in primary cervical and cervical cancer tissues.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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