The Effect of Polyphenolics in Extracts from Natural Materials on Metabolic Activity of Metastatic Melanoma WM-266-4 Cells

Abstract

The importance of natural crops in medicine and pharmacy is growing. Beside bioactive compounds used directly as therapeutic agents, there are also raw materials used for drug synthesis or as a basic model for new biologically active compounds. In this paper, the optimum conditions for material extraction of Curcuma longa, Lycium barbarum, Equisetum arvense, Vitis vinifera, and Rosmarinus officinalis were investigated to achieve high antioxidant levels. The main aim of this study was to verify the correlation between the content of antioxidants, proanthocyanidins and total phenolic substances for certain extracts from the raw materials (Curcuma longa, Lycium barbarum, Equisetum arvense, Vitis vinifera and Rosmarinus officinalis) and the reduction of the metabolic activity of skin cancer cells.

Keywords

• <i>Curcuma longa</i>
• <i>Lycium barbarum</i>
• <i>Equisetum arvense</i>
• <i>Vitis vinifera</i>
• <i>Rosmarinus officinalis</i>
• antioxidant activity