Nature Communications (Oct 2018)

Direct observation of selective autophagy induction in cells and tissues by self-assembled chiral nanodevice

  • Maozhong Sun,
  • Tiantian Hao,
  • Xiaoyun Li,
  • Aihua Qu,
  • Liguang Xu,
  • Changlong Hao,
  • Chuanlai Xu,
  • Hua Kuang

DOI
https://doi.org/10.1038/s41467-018-06946-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Chiral assemblies have gained great interest for probing intracellular effects. Here, the authors report on the development of an upconversion nanoparticle-centred yolk-shell nanoparticle tetrahedron for the induction of autophagy and the monitoring of ATP levels both in living cells and in vivo.