Nature Communications (Aug 2019)

Diurnal rhythms in gene expression in the prefrontal cortex in schizophrenia

  • Marianne L. Seney,
  • Kelly Cahill,
  • John F. Enwright,
  • Ryan W. Logan,
  • Zhiguang Huo,
  • Wei Zong,
  • George Tseng,
  • Colleen A. McClung

DOI
https://doi.org/10.1038/s41467-019-11335-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Sleep disturbance is common in psychiatric disease, and this may contribute to altered circadian rhythm in gene expression. Here the authors show that rhythms in gene expression in the dorsolateral prefrontal cortex in schizophrenia are different to that seen in healthy controls.