Neurospine (Sep 2019)

Does Ossification of the Posterior Longitudinal Ligament Progress After Fusion?

  • Sasha Vaziri,
  • Dennis Timothy Lockney,
  • Alexander B. Dru,
  • Adam J. Polifka,
  • W. Christopher Fox,
  • Daniel J. Hoh

DOI
https://doi.org/10.14245/ns.1938286.143
Journal volume & issue
Vol. 16, no. 3
pp. 483 – 491

Abstract

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Starting in the 1960s, ossification of the posterior longitudinal ligament (OPLL) became more commonly diagnosed in Japan. The disease is characterized by a gradual increase in calcification of the posterior longitudinal ligament with the eventual sequelae of cervical canal stenosis and myelopathy. Surgical interventions to relieve stenosis and neurologic symptoms are performed to decompress the cervical canal. Studies demonstrate continued ossification of the OPLL in both nonsurgical and surgically treated patients. In this review, the authors evaluate the epidemiology, pathophysiology, and literature regarding disease progression in OPLL after cervical fusion.

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