Nature Communications (Jan 2023)

Endosomal sorting results in a selective separation of the protein corona from nanoparticles

  • Shen Han,
  • Richard da Costa Marques,
  • Johanna Simon,
  • Anke Kaltbeitzel,
  • Kaloian Koynov,
  • Katharina Landfester,
  • Volker Mailänder,
  • Ingo Lieberwirth

DOI
https://doi.org/10.1038/s41467-023-35902-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 12

Abstract

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Protein corona formation on nanoparticles and the resultant effects on cellular interactions is well documented, where less is known about the fate of the corona in the cell. Here, the authors track the protein corona and nanoparticles in cells and describe the separation and different processing within different cellular compartments.