iScience (Nov 2023)
Co-registration of OPM-MCG signals with CT using optical scanning
- Yanfei Yang,
- Huidong Wang,
- Zhanyi Liu,
- Yanmei Wang,
- Xiaole Han,
- Yifan Jia,
- Jiaojiao Pang,
- Fei Xie,
- Dexin Yu,
- Yang Zhang,
- Min Xiang,
- Xiaolin Ning
Affiliations
- Yanfei Yang
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Huidong Wang
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Zhanyi Liu
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Yanmei Wang
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Xiaole Han
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Yifan Jia
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China
- Jiaojiao Pang
- Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; Department of Emergency Medicine, Qilu Hospital of Shandong University, Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Jinan 250014, China; National Innovation Platform for Industry-Education Intearation in Medicine-Engineering Interdisciplinary, Shandong University, Jinan 250014, China
- Fei Xie
- Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; Department of Emergency Medicine, Qilu Hospital of Shandong University, Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Jinan 250014, China; National Innovation Platform for Industry-Education Intearation in Medicine-Engineering Interdisciplinary, Shandong University, Jinan 250014, China
- Dexin Yu
- Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; National Innovation Platform for Industry-Education Intearation in Medicine-Engineering Interdisciplinary, Shandong University, Jinan 250014, China; Department of Radiology, Qilu Hospital of Shandong University, Jinan 250014, China
- Yang Zhang
- Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; National Innovation Platform for Industry-Education Intearation in Medicine-Engineering Interdisciplinary, Shandong University, Jinan 250014, China; Department of Radiology, Qilu Hospital of Shandong University, Jinan 250014, China
- Min Xiang
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; Hangzhou Institute of National Extremely-weak Magnetic Field Infrastructure, Hangzhou 310028, China; Hefei National Laboratory, Hefei 230088, China; State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou 510006, China; Corresponding author
- Xiaolin Ning
- Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China; Zhejiang Provincial Key Laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology, Hangzhou Innovation Institute, Beihang University, Hangzhou 310051, China; Shandong Key Laboratory for Magnetic Field-free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine & Functional Imaging, Shandong University, Jinan 250014, China; Hangzhou Institute of National Extremely-weak Magnetic Field Infrastructure, Hangzhou 310028, China; Hefei National Laboratory, Hefei 230088, China; State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou 510006, China; Corresponding author
- Journal volume & issue
-
Vol. 26,
no. 11
p. 108235
Abstract
Summary: Magnetocardiography (MCG) can be used to noninvasively measure the electrophysiological activity of myocardial cells. The high spatial resolution of magnetic source localization can precisely determine the location of cardiomyopathy, which is of great significance for the diagnosis and treatment of cardiovascular disease. To perform magnetic source localization, MCG data must be co-registered with anatomical images. We propose a co-registration method that can be applied to OPM-MCG systems. In this method, the sensor array and the trunk of the subject are scanned using structured light-scanning technology, and the scan results are registered with the reconstructed structure using computed tomography (CT). This can increase the number of effective cloud points acquired and reduce the interference from respiratory motion. The scanning bed of the OPM-MCG system was modified to be consistent with the CT device, ensuring that the state of the body remains consistent between the cardiac magnetometry measurements and CT scans.
