Frontiers in Pharmacology (Feb 2020)
Ethnopharmacological Applications Targeting Alcohol Abuse: Overview and Outlook
- Laxman Singh,
- Tanuj Joshi,
- Devesh Tewari,
- Devesh Tewari,
- Javier Echeverría,
- Andrei Mocan,
- Archana N. Sah,
- Emil Parvanov,
- Nikolay T. Tzvetkov,
- Nikolay T. Tzvetkov,
- Zheng Feei Ma,
- Zheng Feei Ma,
- Yeong Yeh Lee,
- Piotr Poznański,
- Lukasz Huminiecki,
- Mariusz Sacharczuk,
- Artur Jóźwik,
- Jarosław O. Horbańczuk,
- Joanna Feder-Kubis,
- Atanas G. Atanasov,
- Atanas G. Atanasov,
- Atanas G. Atanasov,
- Atanas G. Atanasov
Affiliations
- Laxman Singh
- Centre for Biodiversity Conservation & Management, G.B. Pant National Institute of Himalayan Environment & Sustainable Development, Almora, India
- Tanuj Joshi
- Department of Pharmaceutical Sciences, Faculty of Technology, Kumaun University Bhimtal Campus, Nainital, India
- Devesh Tewari
- Department of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India
- Devesh Tewari
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Javier Echeverría
- Department of Environmental Sciences, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago, Chile
- Andrei Mocan
- Department of Pharmaceutical Botany, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
- Archana N. Sah
- Department of Pharmaceutical Sciences, Faculty of Technology, Kumaun University Bhimtal Campus, Nainital, India
- Emil Parvanov
- Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Division BIOCEV, Prague, Czechia
- Nikolay T. Tzvetkov
- Institute of Molecular Biology “Roumen Tsanev”, Department of Biochemical Pharmacology and Drug Design, Bulgarian Academy of Sciences, Sofia, Bulgaria
- Nikolay T. Tzvetkov
- Department Global R&D, NTZ Lab Ltd., Sofia, Bulgaria
- Zheng Feei Ma
- 0Department of Public Health, Xi’an Jiaotong-Liverpool University, Suzhou, China
- Zheng Feei Ma
- 1School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
- Yeong Yeh Lee
- 1School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
- Piotr Poznański
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Lukasz Huminiecki
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Mariusz Sacharczuk
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Artur Jóźwik
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Jarosław O. Horbańczuk
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Joanna Feder-Kubis
- 2Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego, Wrocław, Poland
- Atanas G. Atanasov
- Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
- Atanas G. Atanasov
- 3Department of Pharmacognosy, University of Vienna, Vienna, Austria
- Atanas G. Atanasov
- 4Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria
- Atanas G. Atanasov
- 5Ludwig Boltzmann Institute for Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria
- DOI
- https://doi.org/10.3389/fphar.2019.01593
- Journal volume & issue
-
Vol. 10
Abstract
Excessive alcohol consumption is the cause of several diseases and thus is of a major concern for society. Worldwide alcohol consumption has increased by many folds over the past decades. This urgently calls for intervention and relapse counteract measures. Modern pharmacological solutions induce complete alcohol self-restraint and prevent relapse, but they have many side effects. Natural products are most promising as they cause fewer adverse effects. Here we discuss in detail the medicinal plants used in various traditional/folklore medicine systems for targeting alcohol abuse. We also comprehensively describe preclinical and clinical studies done on some of these plants along with the possible mechanisms of action.
Keywords
