Urology Case Reports (Mar 2015)

A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab

  • Tomohiro Kanamaru,
  • Taro Iguchi,
  • Nao Yukimatsu,
  • Yasuomi Shimizu,
  • Yuki Kohyama,
  • Hirokazu Tachibana,
  • Minoru Kato,
  • Takeshi Yamasaki,
  • Satoshi Tamada,
  • Tatsuya Nakatani

DOI
https://doi.org/10.1016/j.eucr.2014.11.004
Journal volume & issue
Vol. 3, no. 2
pp. 9 – 11

Abstract

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A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab.

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