Single-cell transcriptomics combined with proteomics of intrathecal IgG reveal transcriptional heterogeneity of oligoclonal IgG-secreting cells in multiple sclerosis

• Justyna Polak,
• Justyna Polak,
• Justyna Polak,
• Johanna H. Wagnerberger,
• Silje Bøen Torsetnes,
• Ida Lindeman,
• Ida Lindeman,
• Rune A. Aa. Høglund,
• Rune A. Aa. Høglund,
• Frode Vartdal,
• Frode Vartdal,
• Ludvig M. Sollid,
• Ludvig M. Sollid,
• Ludvig M. Sollid,
• Andreas Lossius,
• Andreas Lossius,
• Andreas Lossius

Affiliations

Justyna Polak

Department of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway

Justyna Polak

K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway

Justyna Polak

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

Johanna H. Wagnerberger

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

Silje Bøen Torsetnes

Department of Neurology, Akershus University Hospital, Lørenskog, Norway

Ida Lindeman

Department of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway

Ida Lindeman

K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway

Rune A. Aa. Høglund

Department of Neurology, Akershus University Hospital, Lørenskog, Norway

Rune A. Aa. Høglund

Institute of Clinical Medicine, University of Oslo, Oslo, Norway

Frode Vartdal

Department of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway

Frode Vartdal

K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway

Ludvig M. Sollid

Department of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway

Ludvig M. Sollid

K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway

Ludvig M. Sollid

Institute of Clinical Medicine, University of Oslo, Oslo, Norway

Andreas Lossius

K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway

Andreas Lossius

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

Andreas Lossius

Department of Neurology, Akershus University Hospital, Lørenskog, Norway