Nature Communications (Nov 2021)

Cell-fate transition and determination analysis of mouse male germ cells throughout development

  • Jiexiang Zhao,
  • Ping Lu,
  • Cong Wan,
  • Yaping Huang,
  • Manman Cui,
  • Xinyan Yang,
  • Yuqiong Hu,
  • Yi Zheng,
  • Ji Dong,
  • Mei Wang,
  • Shu Zhang,
  • Zhaoting Liu,
  • Shuhui Bian,
  • Xiaoman Wang,
  • Rui Wang,
  • Shaofang Ren,
  • Dazhuang Wang,
  • Zhaokai Yao,
  • Gang Chang,
  • Fuchou Tang,
  • Xiao-Yang Zhao

DOI
https://doi.org/10.1038/s41467-021-27172-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 20

Abstract

Read online

The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for prenatal cell-fate determination.