Engineering Saccharomyces cerevisiae for co-utilization of d-galacturonic acid and d-glucose from citrus peel waste

Ryan J. Protzko; Luke N. Latimer; Ze Martinho; Elise de Reus; Tanja Seibert; J. Philipp Benz; John E. Dueber

doi:10.1038/s41467-018-07589-w

Nature Communications (Nov 2018)

Engineering Saccharomyces cerevisiae for co-utilization of d-galacturonic acid and d-glucose from citrus peel waste

Ryan J. Protzko,
Luke N. Latimer,
Ze Martinho,
Elise de Reus,
Tanja Seibert,
J. Philipp Benz,
John E. Dueber

Affiliations

Ryan J. Protzko: Department of Molecular and Cell Biology, University of California
Luke N. Latimer: Department of Chemistry, University of California
Ze Martinho: Department of Bioengineering, University of California
Elise de Reus: Department of Biotechnology and Biomedicine, Technical University of Denmark
Tanja Seibert: Holzforschung München, TUM School of Life Sciences Weihenstephan, Technische Universität München
J. Philipp Benz: Holzforschung München, TUM School of Life Sciences Weihenstephan, Technische Universität München
John E. Dueber: Department of Bioengineering, University of California

DOI: https://doi.org/10.1038/s41467-018-07589-w
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 10

Abstract

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Pectin-rich agricultural byproducts are ideal feedstocks for biobased chemicals production. Here, the authors engineer the yeast, S. cerevisiae, in several steps to co-utilize d-galacturonic acid and d-glucose and demonstrate the potential of producing meso-galactaric acid from industrial orange peel.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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