Prediction for vascular mild cognitive impairment using the p300 event-related potentials technique

Abstract

Evoked potentials technique owing to informativeness and diagnostic value is widely used in clinical and experimental studies. Herein, we investigated whether the auditory P300 event-related potentials predict syndrome vascular mild cognitive impairment. 42 patients with I and II stages of discirulatory encephalopathy (50-70 years) included in clinical study. The discriminant analysis method was used to work out an equation with two variables as predictors - the P300 latent period and patient's age. The diagnostic accuracy of the discriminant equation at a cut-off -0,268 was established through receiver operating characteristic (ROC) analysis (sensitivity 80%, specificity 74,1%).

Keywords

• умеренные когнитивные расстройства
• когнитивные расстройства цереброваскулярной этиологии
• слуховые когнитивные вызванные потенциалы р300
• латентный период р300
• mild cognitive impairment
• vascular cognitive impairment
• the auditory p300 event-related potentials
• p300 latent period