Nature Communications (May 2018)

Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis

  • Mugdha Sathe,
  • Gayatri Muthukrishnan,
  • James Rae,
  • Andrea Disanza,
  • Mukund Thattai,
  • Giorgio Scita,
  • Robert G. Parton,
  • Satyajit Mayor

DOI
https://doi.org/10.1038/s41467-018-03955-w
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 16

Abstract

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Several endocytic pathways operate simultaneously at the cell surface, including the clathrin and dynamin-independent CLIC/GEEC (CG) pathway. Here the authors show that small GTPases and BAR domain proteins regulate branched actin to make clathrin and dynamin-independent endocytic vesicles.