Correlations between clinico-pathological and prognostic parameters in patients with rectal cancer

Abstract

The objective of this paper was to find correlations between clinico-pathological parameters and survival and tumor recurrence indices with the purpose of improving treatment results and asses better the prognosis of the patients with rectal cancer. The study included 69 patients with rectal cancer in stages I-III according to the AJCC classification (8th edition), who didn’t undergo neoadjuvant treatment and were operated (curative surgery) in the General Department of the Emergency Clinical Hospital Bucharest in a period of 2 years, 01.01.2016 – 31.12.2017. Our statistical analysis showed significant correlations between the quality of the mesorectum and tumor localization, type of surgery or overall survival. Also, we registered important associations between the N stage from TNM classification and tumor grading or lymphovascular invasion. In conclusion, we can say that these correlations observed in our study between clinico-pathological and prognostic parameters in patients with rectal cancer are useful in the treatment and for determining the outcome of these patients.

Keywords

• rectal cancer
• mesorectum
• grading
• lymphovascular invasion