Intergenic splicing-stimulated transcriptional readthrough is suppressed by nonsense-mediated mRNA decay in Arabidopsis

Yukio Kurihara; Yuko Makita; Masaharu Kawauchi; Ami Kageyama; Tomoko Kuriyama; Minami Matsui

doi:10.1038/s42003-022-04348-y

Communications Biology (Dec 2022)

Intergenic splicing-stimulated transcriptional readthrough is suppressed by nonsense-mediated mRNA decay in Arabidopsis

Yukio Kurihara,
Yuko Makita,
Masaharu Kawauchi,
Ami Kageyama,
Tomoko Kuriyama,
Minami Matsui

Affiliations

Yukio Kurihara: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science
Yuko Makita: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science
Masaharu Kawauchi: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science
Ami Kageyama: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science
Tomoko Kuriyama: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science
Minami Matsui: Synthetic Genomics Research Group, RIKEN Center for Sustainable Resource Science

DOI: https://doi.org/10.1038/s42003-022-04348-y
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 10

Abstract

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Readthrough transcripts (RTs) are identified in the genome of Arabidopsis using a long-read sequencing technology and structural and fate examination reveals that RTs are post-transcriptionally regulated by splicing, transcription termination and NMD.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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