Drug Delivery (Dec 2022)

Metal nanoparticles as a promising technology in targeted cancer treatment

  • Jia-Jie Xu,
  • Wan-Chen Zhang,
  • Ya-Wen Guo,
  • Xiao-Yi Chen,
  • You-Ni Zhang

DOI
https://doi.org/10.1080/10717544.2022.2039804
Journal volume & issue
Vol. 29, no. 1
pp. 664 – 678

Abstract

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Traditional anticancer treatments have several limitations, but cancer is still one of the deadliest diseases. As a result, new anticancer drugs are required for the treatment of cancer. The use of metal nanoparticles (NPs) as alternative chemotherapeutic drugs is on the rise in cancer research. Metal NPs have the potential for use in a wide range of applications. Natural or surface-induced anticancer effects can be found in metals. The focus of this review is on the therapeutic potential of metal-based NPs. The potential of various types of metal NPs for tumor targeting will be discussed for cancer treatment. The in vivo application of metal NPs for solid tumors will be reviewed. Risk factors involved in the clinical application of metal NPs will also be summarized.

Keywords