Comparative vascular effects of levetiracetam and valproate with hyperhomocysteinemia in rat models

Abstract

Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this relationship, our study investigates the combined effects of HHcy and antiepileptics on vascular function using a rat model.

Keywords

• hyperhomocysteinemia
• anticonvulsants
• organ bath
• vascular damage
• epilepsy treatment