Choice of rational tactics of treatment of bacterial vaginosis

Abstract

The study involved 49 patients aged 20 to 35 years old, seeking antenatal care with complaints about the presence of vaginal discharge, with a characteristic odor. Verification of the diagnosis of bacterial vaginosis was based on clinical, laboratory examination: Amsel criteria, direct microscopic study, polymerase chain reaction (PCR) in real time. Patients were divided into 2 groups, depending on the results of the clinical course and laboratory data. Group 1 consisted of 25 patients who during the PCR method in real time revealed the presence of moderate vaginal dysbiosis, with a predominance of anaerobic flora. To this group of patients Neo-Penotran® was administered for 7 days. The group 2 included 24 patients who during diagnosis by PCR revealed the presence of vaginal dysbiosis pronounced, with a predominance of mixed dysbiosis. To this group of patients, we administered a combined preparation of Neo-Penotran® Forte (7 days). The results obtained indicate the absence of relapse within 3 months after therapy. Therefore, during diagnosis and the verification of a diagnosis of bacterial vaginosis is necessary to estimate the degree of vaginal dysbacteriosis using, including but routine methods, polymerase chain reaction, real-time. Appointment of treatments for bacterial vaginosis should be commensurate with the violations of the habitat of the vagina.

Keywords

• bacterial vaginosis
• amsel criteria
• the polymerase chain reaction in real time
• the preparations of 5-nitroimidazoles
• neo-penotran