The Augmented Productions of Neopterin and Cytokines from Macrophages/monocytes in vitro

Abstract

In Kawasaki disease patients, increases in excretion of urinary neopterin coincided with fever and monocytosis in peripheral blood. We examined the products of neopterin, tumor necrosis factor-α (TNFα) and Interleukin-1 β (1L-1β) from healthy adult macrophages/monocytes (Mφ>/M), after stimulation with several activators to obtain some understanding of Kawasaki disease.

Keywords

• neopterin
• cytokines
• endothelial ceil
• monocyte