BrewerIX enables allelic expression analysis of imprinted and X-linked genes from bulk and single-cell transcriptomes

Affiliations

Paolo Martini: Department of Biology, University of Padova
Gabriele Sales: Department of Biology, University of Padova
Linda Diamante: Department of Molecular Medicine, Medical School, University of Padova
Valentina Perrera: Department of Molecular Medicine, Medical School, University of Padova
Chiara Colantuono: Telethon Institute of Genetics and Medicine (TIGEM), Armenise/Harvard Laboratory of Integrative Genomics
Sara Riccardo: Telethon Institute of Genetics and Medicine (TIGEM), Armenise/Harvard Laboratory of Integrative Genomics
Davide Cacchiarelli: Telethon Institute of Genetics and Medicine (TIGEM), Armenise/Harvard Laboratory of Integrative Genomics
Chiara Romualdi: Department of Biology, University of Padova
Graziano Martello: Department of Biology, University of Padova

Abstract

BrewerIX is an easy-to-use computational tool that can assess bi-allelic expression of imprinted and X-linked genes from RNA-seq data.