Experimental Infection of North American Deer Mice with Clade I and II Monkeypox Virus Isolates

Abstract

The global spread of monkeypox virus has raised concerns over the establishment of novel enzootic reservoirs in expanded geographic regions. We demonstrate that although deer mice are permissive to experimental infection with clade I and II monkeypox viruses, the infection is short-lived and has limited capability for active transmission.

Keywords

• mpox
• monkeypox
• MPXV
• viruses
• deer mouse
• experimental infection